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African Health Sciences ; 23(1):72-82, 2023.
Article in English | EMBASE | ID: covidwho-2312182

ABSTRACT

Background: Data regarding the features and outcomes of hospitalized COVID-19 patients in Africa are increasingly available. Objective(s): To describe socio-demographic, clinical and laboratory characteristics and outcomes of COVID-19 patients. Method(s): A cross-sectional study of 86 adult patients hospitalized with COVID-19 between March and November 2020. Characteristics were described in survivors and non-survivors. Result(s): Mean age was 60.9+/-16.1 years, 53(61.6%) were male. Co-morbidities were found in 77(89.5%) patients. On severity, 6(7%) were mild, 23(26.7%) moderate, 51(59.3%) severe and 6(7%) critical. Oxygen saturation and respiratory rate were 71+/-22% and 38+/-11/minute in non-survivors and 90+/-7% and 31+/-7/minute in survivors respectively (p<0.001, p<0.001)). Overall mortality was 47.7% with no death among patients with mild disease and deaths in all patients with critical disease. Duration of hospitalization was 2.0(1.0-4.5) days in those who died and 12(7.0-15.0) days in those who survived (p<0.001). Of the 42 patients that received dexamethasone, 11(26.2%) died, while 31(73.8%) survived (p=<0.001). Conclusion(s): Most of the patients had co-morbidities and there was high mortality in patients with severe and critical COVID-19. Mean oxygen saturation was low and respiratory rate high overall. Factors associated with mortality included: Significantly greater hypoxia and tachypnea, less dexamethasone use and shorter hospitalization.Copyright © 2023 Adekanmbi O et al. Licensee African Health Sciences.

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